Point-of-Care Intrapartum Group B Streptococcus Molecular Screening
نویسندگان
چکیده
منابع مشابه
Significance of Gram's Stain in Rapid Intrapartum Screening for Maternal Carriership of Group B Streptococcus
OBJECTIVE Group B streptococcus (GBS, Streptococcus agalactiae) is an important cause of neonatal sepsis. Prevention is possible by intrapartum screening for maternal GBS carriership and antimicrobial treatment of colonized women with risk factors during labor. The conflicting results of diagnostic performance are reported both for the newly developed rapid GBS antigen tests and Gram's stain. ...
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Traditionally, the capsular polysaccharide (CPS) antigen has been used to distinguish between the nine known serotypes of group B streptococcus (GBS) by classical antibody-antigen reactions. In this study, we used PCR for all CPSs and selected protein antigens, multilocus sequencing typing (MLST), and pulsed-field gel electrophoresis (PFGE) to molecularly characterize 92 clinical isolates ident...
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BACKGROUND Group B streptococcal disease is one of the most common infections in the first week after birth. In 2002, national guidelines recommended universal late antenatal screening of pregnant women for colonization with group B streptococcus to identify candidates for intrapartum chemoprophylaxis. METHODS We evaluated the implementation of the guidelines in a multistate, retrospective co...
متن کاملReal-time PCR assay provides reliable assessment of intrapartum carriage of group B Streptococcus.
The objective of this study was to determine the reliability of the real-time PCR assay for determining the group B Streptococcus (GBS) status of women in labor. In this prospective study we compared the results of culture and PCR testing of vaginal and rectal samples collected by nursing staff when women were in labor. Patients' charts were also reviewed to obtain relevant information about pr...
متن کاملDuration of Intrapartum Antibiotics for Group B Streptococcus on the Diagnosis of Clinical Neonatal Sepsis
BACKGROUND Infants born to mothers who are colonized with group B streptococcus (GBS) but received <4 hours of intrapartum antibiotic prophylaxis (IAP) are at-risk for presenting later with sepsis. We assessed if <4 hours of maternal IAP for GBS are associated with an increased incidence of clinical neonatal sepsis. MATERIALS AND METHODS A retrospective cohort study of women-infant dyads unde...
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ژورنال
عنوان ژورنال: Obstetrics & Gynecology
سال: 2019
ISSN: 0029-7844
DOI: 10.1097/aog.0000000000003057